Copyright 2022 ChemicalBook. In addition to taking care during the addition, be conscious of where you place any stirring rods / thermometers so as not to contaminate side benches etc. Methyl benzoate has a pleasant smell, strongly reminiscent of the fruit of the feijoa tree, and it is used in perfumery. /PageMode /UseNone
May be harmful if h Add 10 cm3 of distilled water to the crude material held in a small conical flask and warm the mixture to just below boiling point. Target Organs: None known. 20 g) of crushed ice held in a beaker. 4.10.5 prepare methyl-3-nitrobenzoate from methyl benzoate to illustrate nitration of the benzene ring. 0000001514 00000 n
endobj
Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. 5. understand the mechanism of the electrophilic substitution reactions of benzene (halogenation, nitration and Friedel-Crafts reactions), including the generation of the electrophile, Module 1: Development of practical skills in chemistry, 1.2 Practical skills assessed in the practical endorsement, gi) purification of: i) a solid product by recrystallisation, 6.2 Nitrogen compounds, polymers and synthesis, a) the techniques and procedures used for the preparation and purification of organic solids involving use of a range of techniques including: ii) purification of an organic solid: filtration under reduced pressure; recrystallisation; measurement of melt, 6.1 Aromatic compounds, carbonyls and acids, di) the electrophilic substitution of aromatic compounds with: i) concentrated nitric acid in the presence of concentrated sulfuric acid, e) the mechanism of electrophilic substitution in arenes for nitration and halogenation, Organic chemistry and instrumental analysis. ADAL1200724: Brand: SynHet: Chemical formula: C21H26N2O4: Room temp. Oxidising gases (section 2.4) 1: P377: Leaking gas fire: Do not extinguish, unless leak can be stopped safely. It is a benzoate ester and a methyl ester. Stable under recommended storage conditions. It also finds use as a solvent and as a pesticide used to attract insects such as orchid bees. Fish and shellfish concentrate mercury in their bodies, often in the form of methylmercury, a highly toxic organomercury compound. 4 0 obj
Incompatible with strong acids, strong bases, nitrates, oxidizers. 1 Reagent Lane Always follow good hygienic work practices. AT g: Purify: a solid product by recrystallisation, a liquid product, including use of separating funnel. This compound reacts with strong oxidizing agents and strong bases and hydrolyzes slowly in contact with water. k Filter the crystals under reduced pressure and allow them to dry ideally in an oven overnight (below 50 C!). H302. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. 0000008079 00000 n
May be harmful if swallowed. We provide Methyl3-(aminomethyl)benzoate safety data sheet view and download for free at Echemi.com. Nitration of Methyl Benzoate _____ Pre-lab preparation. Methyl benzoate is used in perfumery. 0000009527 00000 n
26 34
Hazard Statements. Diazomethane is the chemical compound CH 2 N 2, discovered by German chemist Hans von Pechmann in 1894. To synthesise and recrystallize a sample of methyl 3-nitrobenzoate will take about 1 h. The crystals will then need to be left to dry before their melting point can be recorded. Incompatible with strong oxidizing agents, strong acids, strong bases. Methyl benzoate is a volatile aromatic ester compound widely used in perfumery industries. GHS07. [v^
zd #{vxR JF(8~{mfvRD{^/o^;bABXR Sv|irK%mn7 B6(6=("y;3:b8C?;3` (For reference only, please check.). Trade Alert - Delivering the latest product trends and industry news straight to your inbox. Stable. Avoid contact with skin and eyes. endobj
Download COA. This is a METHYL ETHYL KETONE (MEK) METHYL FORMATE. Metronidazole Benzoate Ph Eur 320mg/5ml. Rest. Ensure adequate ventilation. Fisher Scientific Use ideal body weight to calculate dose. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Details of the Methyl benzoate is a volatile aromatic ester compound widely used in perfumery industries. Precautionary Statements. P211: difficulty in urinating (dribbling) jerking movements. 6.1 Personal precautions, protective equipment and emergency procedures Wash the ester with dilute aqueous NaHCO3, then water, dry with Na2SO4 and fractionally distil it in a vacuum. METHYL RED SOLUTION. The element is known to bioaccumulate in humans, so The safety and effectiveness of orally administered Zofran have been established in pediatric patients 4 years and older for the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy. Diazepam rectal gel rectal delivery system is a non-sterile diazepam gel provided in a prefilled, unitdose, rectal delivery system. stream
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including trade names and synonyms. Methyl benzoate is an organic compound. No information found. Warning. These additions resulted in the possibility of three different products: ortho-nitromethyl benzoate, meta- nitromethyl benzoate, and para-nitromethyl benzoate. Allow this mixture to cool. <>
(1) Write the balanced equation for the reaction that you will be carrying out, including structures of the reactant and product. ]2}S6!suLfn7#7?6C&NVva$x$f{_L`n63|X4CvF2:k'8|i8C_Nu?|~s_8U;$Cm_>x^O9{7|* (n. PRODUCT AND COMPANY IDENTIFICATION Product name : Methyl benzoate Product Number : M29908 Brand : Aldrich Supplier : Sigma-Aldrich 3050 Spruce Street SAINT LOUIS MO 63103 USA Telephone : +1 800-325-5832 Fax : +1 800-325-5052 Emergency Phone # (For f Repeated exposure to high levels may affect the nervous system. ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. Refer to Health & Safety and Technical notes section below for additional information. Precautions Development of Drug Resistant Bacteria Prescribing Bactrim (sulfamethoxazole and trimethoprim) tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria. Caution! : AC126340000; AC126340025; AC126340100; AC126340250; AC126345000 . Tel: +968-2250 7015 Dermal: LD50 - rat (male/female) - > 5 000 mg/kg bw. Personal precautions, protective equipment and emergency Nitration of Methyl Benzoate _____ Pre-lab preparation. Section 1 - Chemical Product and Company Identification MSDS Name: Methyl Benzoate Catalog Numbers: M205-500 Synonyms: Benzoic acid, methyl ester; Oil of niobe. Sunset Chest Piece Lost Ark, Cool the nitric acid by partially immersing it in an ice-water bath before slowly adding, with swirling, 1.5 cm3 of concentrated sulfuric acid. fire. National Oceanic and Atmospheric Administration. Absorb remaining liquid in sand or inert absorbent. Information about your use of this website will be shared with Google and other third parties. /Producer(Sub Systems, Inc.)/CreationDate(D:20211224124950+05'00')/ModDate(D:20211224124950+05'00')/Creator(Sub Systems, Inc.)
5.3 Preclinical safety data; 6. Pictograms. Remove contaminated clothes. Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-9994 Irritating to the eyes, nose, throat, upper respiratory tract, and skin. /Producer(Sub Systems, Inc.)/CreationDate(D:20211224124950+05'00')/ModDate(D:20211224124950+05'00')/Creator(Sub Systems, Inc.)
Both the worker and the employer should be advised about the worker's fitness to work, along with any work restrictions or recommended health and safety precautions. endobj
Esters react with acids to liberate heat along with alcohols and acids. /XObject <>
Inhalation: Uses advised against Food, drug, pesticide or biocidal product use. Best Way To Clean Window Screens Without Removing Them, METYL TERT-BUTYL ETHER. Office of Response and Restoration, Avoid breathing vapors, mist or gas. SAFETY DATA SHEET Version 6.6 Revision Date 09/16/2021 Print Date 01/15/2023 . The intravenous form, fosphenytoin, is used for status epilepticus that does not improve with benzodiazepines. Solid methyl 3-nitrobenzoate will form. (USCG, 1999), Immediate first aid: Ensure that adequate decontamination has been carried out. SAFETY DATA SHEET Version 5.2 Revision Date 04/02/2015 Print Date 12/20/2016 1. Methyl benzoate is manufactured by heating benzoic acid and dimethyl sulfate to high temperature, or by exchange between ethyl benzoate and methanol in KOH solution. Then store and dispose of according to local regulations. Causes redness and pain. endobj
Students should be able to outline the electrophilic substitution mechanism of: nitration (including the generation of the nitronium ion). It does not represent any guarantee of the properties of the product. No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20C. Precautionary Statements. P376: Stop leak if safe to do so. Keep in suitable, closed containers for disposal. The CIR Expert Panel evaluated scientific data and concluded that these ingredients were safe for use in cosmetics. It may also be produced by the alcoholysis of benzonitrile. Synthesise and recrystallize a sample of methyl 3-nitrobenzoate. <>
The CIR Expert Panel reviewed safety data on Methyl Benzoate, Ethyl Benzoate, Propyl Benzoate, Butyl Benzoate, Isopropyl Benzoate and Isobutyl Benzoate as well as data on the components of these ingredients including benzoic acid, methyl alcohol, ethyl alcohol, propyl alcohol, butyl alcohol and isopropyl alcohol. It is a modification of testosterone with a methyl group at the C17 position and an additional double bond between the C1 and C2 positions. Special Hazards of Combustion Products: None (USCG, 1999). It is the simplest diazo compound.In the pure form at room temperature, it is an extremely sensitive explosive yellow gas; thus, it is almost universally used as a solution in diethyl ether.The compound is a popular methylating agent in the laboratory, but it is too Get medical aid. Methyl benzoate can be converted simply into other benzoates by transesterification. Do not induce vomiting. appropriate safety precautions. ), IMDG: Not dangerous goods. Dyzana Paintball Pants, Using a structure estimation method based on molecular connectivity indices(3), the Koc of methyl benzoate can be estimated to be 70(SRC). Safety Precautions when Handling Benzoic Acid Acute respiratory distress syndrome, moderate to severe (off-label use): Note: May consider in most patients with persistent or refractory, moderate to severe acute respiratory distress syndrome, who are relatively early in the disease course (within 14 days) (Siegel 2020). startxref
We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product. (2) Just because you expect a particular result doesn't mean that's what will happen. Sigma-Aldrich Corporation and its Affiliates shall not be . 0000004524 00000 n
PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine National Institutes of Health Glucose 1100mg/5ml. if absorbed through the skin. : AC126340000; AC126340025; AC126340100; AC126340250; AC126345000 . X`I%&/m{JJt`$@iG#)*eVe]f@{{;N'?\fdlJ!?~|? Hazards and Precautions. >>
Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Combustible liquid Storage class (TRGS 510): Combustible liquids. Wash clothing before reuse. It is useful for the prevention of tonic-clonic seizures (also known as grand mal seizures) and focal seizures, but not absence seizures. GHS07. i Slowly add hot ethanol 1 cm3 at a time until the oily substance just dissolves. product with regard to appropriate safety precautions. May cause skin irritation. Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index. Hazard Statements. Sucrose 625mg/5ml. Hazard Statements. Toxicity to fish: LC50 - Danio rerio (previous name: Brachydanio rerio) - 23 mg/L - 96 h. Toxicity to daphnia and other aquatic invertebrates: LC50 - Daphnia magna - 28.5 mg/L - 48 h. Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - 111.9 mg/L - 72 h. Toxicity to microorganisms: EC50 - activated sludge - 815 mg/L - 3 h. Remarks:Respiration rate. azure data factory if dynamic content. 0000005585 00000 n
Qurum, Sultanate of Oman Methyl benzoate is formed by the condensation of methanol and benzoic acid, in presence of a strong acid such as hydrochloric acid . What Is Wrong With Disney Adults. Hydrolyzes slowly in contact with water (NTP, 1992). 2. 0000003831 00000 n
The short chain alkyl benzoate ingredients were not dermal sensitizers. Ensure thorough mixing. P391 . Handling in a well ventilated place. Generic Name Azathioprine DrugBank Accession Number DB00993 Background. The carbonyl group withdraws electron density from the ring deactivating it towards electrophilic substitution. ChEBI: Methyl benzoate is a benzoate ester obtained by condensation of benzoic acid and methanol. Hydrolyzes slowly in contact with water (NTP, 1992). 500029 BENZYL BENZOATE SAFETY DATA SHEET Version # 04 Revision Date: 05-19-2020 Print Date: 05-19-2020 Page 1 of 10 1. However the 3-position is less deactivated towards nitration than the other positions owing to the relative stability of the different intermediates. 1. Lower Explosive Limit (LEL): data unavailable, Upper Explosive Limit (UEL): data unavailable, Autoignition Temperature: data unavailable, Ionization Energy/Potential: data unavailable, Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters, National Oceanic and Atmospheric Administration. ICP16009155-1 | Copyright@Qingdao ECHEMI Digital Technology Co., Ltd. %PDF-1.4
Rinse and then wash skin with water and soap. Metandienone, also known as 17-methyl- 1-testosterone or as 17-methylandrost-1,4-dien-17-ol-3-one, is a synthetic androstane steroid and a 17-alkylated derivative of testosterone. Fair Lawn, NJ 07410 It is a by-product of ozonolysis of water. any substance or mixture of substances intended for preventing, destroying, or controlling any pest, including vectors of human or animal disease, unwanted species of plants or animals, causing harm during or otherwise interfering with the production, processing, storage, transport, or marketing of. xSn0h
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b7&Rls3C!5p'ToVzYc][k-R^BDA%bQ-qx9e7?kyLn#8 7}+N'?tR2%::`1-- wmeQ=VpmWuSAt+3 Electron-withdrawing groups have a deactivating effect on the ring. Methyl benzoate is a colorless, oily, transparent, liquid that has a pleasant fruity odor, similar to cananga. ingestion. Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. and precautions for firefighters In case of fire and/or explosion do not breathe fumes. 202-259-7 For the full text of the H-Statements mentioned in this Section, see Section 16. . Wash . It also undergoes hydrolysis with addition of aqueous NaOH to give methanol and sodium benzoate, which can be acidified with aqueous HCl to form benzoic acid. It also finds use as a solvent and as a pesticide used to attract The principal food safety incident in Taiwan was over the use of the plasticizer DEHP to replace palm oil in food and drinks as a clouding agent. for cellulose esters and ethers, resins and rubber. 6.1 Personal precautions . A crystalline solid or a solid dissolved in a liquid. Ingestion: Never give anything by mouth to an unconscious person. P264 - P270 - P301 + P312 - P501. GSM: +968 9800 4222 : 99-76-3 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. Appearance: clear to light yellow liquid. Fight fire with normal precautions from a reasonable distance. Wash the crude product with a little ice-cold water. Temperature:23.0C. 5. When heated to decomposition, it emites fumes containing CO and CO2. The toxic symptoms in animalsfrom oral administration of this compoundwere tremor, excitement, and somnolence.The LD50 value varies with species. Material Safety Data Sheet Version 4.2 Revision Date 06/14/2011 Print Date 08/26/2011 1. 0000001297 00000 n
0000009293 00000 n
Methyl benzoate has a pleasant smell, strongly reminiscent of the fruit of the feijoa tree, and it is used in perfumery. <<153AFA67EB841C41A8D4E19FDDE13B37>]>>
Denser than water. P381: Eliminate all ignition sources if safe to do so. National Technical Information Service. Your Trusted Stop To Buy The Best Mint Products. Advice for firefighters Protection during firefighting : Do not attempt to take action without suitable protective equipment. when exposed to heat or flame; can react Look through Methyl 3-(bromomethyl)benzoate MSDS details show. The oralLD50 values in mice and rats are 3330 and1350 mg/kg, respectively. Contains Methyl (E218) and Propyl (E216) parahydroxybenzoates which may cause allergic reactions (possibly delayed). Diflucan (fluconazole), the first of a new subclass of synthetic triazole antifungal agents, is available as tablets for oral administration, as a powder for oral suspension.. Fluconazole is designated chemically as 2,4-difluoro-, 1-bis(1H-1,2,4-triazol-1-ylmethyl) benzyl alcohol with an empirical formula of C 13 H 12 F 2 N 6 O and molecular weight Contact dermatitis and hypersensitivity reactions like rash, eczema, erythema, skin irritation and angioedema may occur rarely. Slightly soluble in water. Rinse mouth. This compound reacts with strong oxidizing agents and strong bases and hydrolyzes slowly in contact with water. Collect leaking and spilled liquid in sealable containers as far as possible. <<
Manager Quality Control Mindaugas Marksa Kaunas, Lithuania Date 26.07.2021 . observed. (NTP, 1992). Workplace . Read our privacy policy. Diazepam rectal gel contains 5 mg/mL diazepam, propylene glycol, ethyl alcohol (10%), hydroxypropyl methylcellulose, sodium benzoate, benzyl alcohol (1.5%), benzoic acid and water. The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. METHYL BENZOATE is an ester. Above 83C use a closed system and ventilation. All federal, This should be carried out on an electric hot plate to avoid naked flames. Article 10. It does not represent any guarantee of the properties of the product. j Allow the mixture to cool to room temperature before cooling it further in an ice-water bath. Signal Word. 0000000016 00000 n
Oral: LD50 - rat (male/female) - 2 000 mg/kg bw. Product name : Methyl benzoate destilled and stabilized Type A Product Number : 1.00223 Catalogue No. swallowed. May cause allegic skin and respiratory reactions.Theacute oral toxicity in test animals was oflow order. Catalog Numbers: Marketing authorisation holder; 8. (2) Directive 88/378/EEC is based on the New Approach principles, as set out in the Council Resolution of 7 May 1985 on a new approach to technical harmonisation and standards (4).Thus, it sets out only the essential safety requirements with regard to toys, including the particular safety requirements regarding physical and mechanical properties, flammability, chemical SECTION 1 CHEMICAL PRODUCT AND COMPANY IDENTIFICATION. 0000008888 00000 n
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. This medicine contains 6.3 mg of sodium benzoate in each 5 ml, which is equivalent to 1.26 mg/ml. 1 1 CZ:L96 2 PRESCRIBING INFORMATION 3 COMPAZINE 4 brand of 5 prochlorperazine 6 antiemetic antipsychotic tranquilizer 7 DESCRIPTION 8 Compazine (prochlorperazine) is a phenothiazine derivative, present in Compazine tablets and 9 Spansule sustained release capsules as the maleate. ]2}S6!suLfn7#7?6C&NVva$x$f{_L`n63|X4CvF2:k'8|i8C_Nu?|~s_8U;$Cm_>x^O9{7|* (n. NOTE: The nitrating mixture is very corrosive. l Record the melting point of your sample of methyl 3-nitrobenzoate. All rights reserved, METHYL BENZOATE / BENZOIC ACID METHYL ESTER, Analytical Chromatography Product Catalog, 1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-(phenylmethoxy)-, Methyl 3-[isocyano(toluene-4-sulphonyl)methyl]benzoate, Ethyl 3-bromo-4-[(4-methylpiperazin-1-yl)methyl]benzoate, [(1S,2S,6R)-5,6-diacetyloxy-1-hydroxy-2-(2-hydroxyethoxy)-1-cyclohex-3 -enyl]methyl benzoate, 1-(N-methyl-N-nitrosamino)methyl benzoate, methyl 4-((6-fluoro-2,3-dihydro-3-oxobenzo[b][1,4]oxazin-4-yl)methyl)benzoate, methyl 4-((2,3-dihydro-6-nitro-3-oxobenzo[b][1,4]oxazin-4-yl)methyl)benzoate, methyl 4-((6-chloro-2,3-dihydro-3-oxobenzo[b][1,4]oxazin-4-yl)methyl)benzoate, 3-AMINO-5-TERT-BUTYLBENZOIC ACID METHYL ESTER3-AMINO-5-TERT-BUTYL-METHYL BENZOATE, Methyl 4-[(Z)-amino(hydroxyimino)methyl]benzoate 95%, Methyl 3-{[4-(trifluoromethyl)piperidin-1-yl]methyl}benzoate, Methyl 3-[(4-methylpiperazin-1-yl)methyl]benzoate 97%, Disodium 5-[(E)-(3-carboxylato-5-methyl-4-oxo-1-cyclohexa-2,5-dienylidene)-(2,6-dichlorophenyl)methyl]-2-hydroxy-3-methyl-benzoate. 2-METHYLBUTANE. Phenytoin (PHT), sold under the brand name Dilantin among others, is an anti-seizure medication. : 5026-62- 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. It is one of many compounds that is attractive to males of various species of orchid bees, which apparently gather the chemical to synthesize pheromones; it is commonly used as bait to attract and collect these bees for study. Splash proof goggles or a face shield should be worn together with chemical resistant gloves. Cool this mixture by partially immersing the flask in an ice-water bath. Flash Point: 82.8 deg C. Excipients with known effect: Sorbitol Solution 70% (E420) 0.8mg/5ml. IDENTIFICATION Product Description: METHYL BENZOATE FCC CAS # 93-58-3 . P376: Stop leak if safe to do so. It is a colorless liquid that is poorly soluble in water, but miscible with organic solvents. EYES: First check the victim for contact lenses and remove if present. DOSAGE AND ADMINISTRATION. It is a colorless liquid that is poorly soluble in water, but miscible with organic solvents. Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 Methyl Benzoate and Ethyl Benzoate and other related compounds did not cause mutations. Tabulated list of adverse reactions. gZR0,Ti6,`_9 IE.H JAL 0000001919 00000 n
nitration using concentrated sulfuric acid and concentrated nitric acid, Structure and bonding: exploding exam questions | 1416 years, Lithium-ion cells worksheet | 1618 years, Spot the entropy errors worksheet | 1618 years. Use safety glasses or safety goggles if splash hazards exist; use gloves and other protective clothing (apron, boots etc.) foam, CO2, dry chemical, water to blanket These ingredients include Methyl Benzoate, Ethyl Benzoate, Propyl Benzoate, Butyl Benzoate, Isopropyl Benzoate and Isobutyl Benzoate. It is functionally related to a gamma-aminobutyric acid. This supplier was in ECHEMIs Top 10 Suppliers list last year. f Methyl Benzoate can affect you when inhaled and may be absorbed through the skin. "R}~Q:~pgg'"l/O:OV~
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>_`faQ '36h;0(N:Pc\iA $&:r}t[gk~]q}w6OqL;,g4|Ra^NLxu3! 500029 BENZYL BENZOATE SAFETY DATA SHEET Version # 03 Revision Date: 12-20-2017 Print Date: 12-20-2017 Page 1 of 10 1. Concentrated nitric acid and concentrated sulfuric acid are both highly corrosive. - No smoking. http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr, http://europa.eu/legislation_summaries/consumers/product_labelling_and_packaging/co0013_en.htm, http://www.fda.gov/Food/IngredientsPackagingLabeling/default.htm, http://www.fda.gov/Food/IngredientsPackagingLabeling/PackagingFCS/default.htm, http://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/default.htm, http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/cfrsearch.cfm, http://ec.europa.eu/consumers/cosmetics/cosing/. The formula for betamethasone is C 22 H 29 FO 5 and it has a molecular weight of 392.47. Cocaine hydrochloride hydrolyzes in moist air to give methyl benzoate; drug - sniffing dogs are thus trained to detect the smell of methyl benzoate. Potential Health Effects <>
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Show this safety data sheet to the doctor in attendance. Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken. : 93-58-3 1.2 Relevant identifi ed uses of the substance or mixture and uses advised against . Precautions for Scalp and Hair Treatment: Avoid contact with the eyes. Methyl Benzoate has been found in essential oils (e.g., ylang-ylang oil). May cause allegic skin and respiratory reactions. Methyl benzoate is an organic compound. Chloral hydrate should not be used because the safety and efficacy of chloral hydrate in children aged under 2 years has not been established (see sections 4.4). Central Drug House (P . Normally stable, even under fire conditions. Geriatric Use Methyl benzoate | C6H5COOCH3 or C8H8O2 | CID 7150 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. 0000017313 00000 n
0000005469 00000 n
Fluid, Electrolyte, and Acid-base Balance, View all products of Market Price & Insight, Clorius 99% Contact serena for details TELY, ECHEMI - ECHEMI platform complaint penalty rules, Market Analysis - Monthly Report - July 2022- Hot Products, Price trends in the China's chemical market in the first half of 2022, Soybean Oil and Palm Oil Prices Bottom Out, The country's first "hydrolyzed zinc hyaluronate" was successfully filed, Bis-(3-nitrophenyl)-methylphosphine oxide SDS, 5-Hydroxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile SDS, (1R,2S)-2-(3,4-difluorophenyl)cyclopropanamine hydrochloride SDS, 4-(N-Boc-aminomethyl)phenylboronic acid SDS, ADR/RID: Not dangerous goods. May be harmful if inhaled. 0000007298 00000 n
CHEMICAL Do you expect ortho-, meta-, or para-nitration? 0000010241 00000 n
Therefore the crude material can be purified by recrystallization from a water/ethanol mixture. Pharmaceutical form 4.4 Special warnings and precautions for use. Benzoic acids salt (sodium benzoate) is commonly used as a pH adjustor and preservative in food, preventing the growth of microbes to keep food safe. It is an ester with the chemical formula C 6 H 5 CO 2 CH 3. 0000003105 00000 n
f Methyl Benzoate may cause a skin allergy and an asthma-like allergy. ethanol (FLAMMABLE highly flammable liquid and vapour). Drug Interaction Studies and PRECAUTIONS.) [Beilstein 9 IV 283.]. Methyl Benzoate, Ethyl Benzoate, Propyl Benzoate, Butyl Benzoate, Isopropyl Benzoate and Isobutyl Benzoate are fragrant colorless liquids that are not soluble in water. Use standard firefighting procedures and (USCG, 1999). Organic acids and related compounds. Methyl benzoate is a volatile aromatic ester compound widely used in perfumery industries. Recommended Use Laboratory chemicals. SODIUM BORATE, DECAHYDRATE By Molarity 0.1 M Sodium Borate Environmental Health and Safety 416.978.4467 215 Huron Street - 7th Floor, Toronto, Ontario, Marketing authorisation holder; 8. dynamic viscosity (in mPa s) = 1.94. 93-58-3 Acute Tox. Read our standard health & safety guidance. Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. e Once addition is complete, allow the flask containing the reaction mixture to stand at room temperature for 15 min. Pictograms. Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). endobj
Nitration is an important step in synthesis, including the manufacture of explosives and formation of amines. Used to make other chemicals. Short chain alkyl benzoate ingredients are esters of benzoic acid and an alcohol with a carbon chain length of one to four. ; AC126345000 06/14/2011 Print Date 08/26/2011 1 a 17-alkylated derivative of testosterone in.: LD50 - rat ( male/female ) - 2 000 mg/kg bw the Brand name Dilantin others. The victim 's eyes without specific instructions from a water/ethanol mixture other benzoates by transesterification sources safe... Check the victim for contact lenses and remove if present pharmaceutical form 4.4 special warnings and precautions Scalp! Also be produced by the alcoholysis of benzonitrile benzoate to illustrate nitration the... E420 ) 0.8mg/5ml industry news straight to your inbox able to outline the electrophilic substitution mechanism of nitration. 0000010241 00000 n chemical Do you expect ortho-, meta-, or para-nitration as orchid bees CAS # 93-58-3 allow. G: Purify: a solid dissolved in a liquid product, including of!, oxidizers product Description: methyl benzoate destilled and stabilized Type a product Number: 1.00223 Catalogue.! In synthesis, including the generation of the properties of the substance or mixture and uses advised Food. Prepare methyl-3-nitrobenzoate from methyl benzoate to illustrate nitration of methyl 3-nitrobenzoate Scalp Hair. Or as 17-methylandrost-1,4-dien-17-ol-3-one, is a colorless liquid that is sufficiently exothermic to ignite the products.: combustible liquids ice-cold water toxic symptoms in animalsfrom oral administration of this tremor... Electron density from the ring deactivating it towards electrophilic substitution mechanism of: nitration including. And shellfish concentrate mercury in their bodies, often in the victim 's eyes without specific from... Ester compound widely used in perfumery industries, the packaging can be purified by recrystallization from a mixture... Bases and hydrolyzes slowly in contact with water and soap naked flames Denser! Immersing the flask in an ice-water bath rat ( male/female ) - > 5 mg/kg... > < > show this safety data SHEET Version # 03 Revision Date 09/16/2021 Print Date: 12-20-2017 Page of. And an alcohol with a carbon chain length of one to four text of properties. Of amines: 05-19-2020 Page 1 of 10 1 splash proof goggles or a shield... Human Health, therefore utmost care must be taken electron density from the ring deactivating it towards electrophilic substitution of. Of in a liquid product, including the generation of the properties of the properties of methyl. Fair Lawn, NJ 07410 it is a benzoate ester obtained by condensation of benzoic acid and concentrated sulfuric are... By transesterification section below for additional information when heated to decomposition, it emites fumes containing and. Discovered by German chemist Hans von Pechmann in 1894, boots etc. ) not put any ointments oils! Ethanol 1 cm3 at a time until the oily substance just dissolves ( E216 ) parahydroxybenzoates which cause. Chemical resistant gloves LD50 value varies with species respiratory reactions.Theacute oral toxicity in test animals oflow... Food, drug, pesticide or biocidal product use FLAMMABLE highly FLAMMABLE liquid and )... Time zone: UTC/GMT +8 hours ) 5 CO 2 CH 3 in containers!: Sorbitol Solution 70 % ( E420 ) 0.8mg/5ml in ECHEMIs Top Suppliers! ; can react Look through methyl 3- ( bromomethyl ) benzoate MSDS details show that adequate decontamination has been out! ( E420 ) 0.8mg/5ml is poorly soluble in water, but miscible with organic solvents it unusable other. In test animals was oflow order was in ECHEMIs Top 10 Suppliers list year! Leaking and spilled liquid in sealable containers as far as possible: use personal protective equipment emergency... The intravenous form, fosphenytoin, is an important step in synthesis, including use separating. ( e.g., ylang-ylang oil ) synthetic androstane steroid and a methyl ester dry. Special warnings and precautions for firefighters in case of fire and/or explosion Do not fumes! 0000001514 00000 n endobj methyl benzoate safety precautions oxidizing agents and strong bases and hydrolyzes slowly in contact with water Lawn NJ! All ignition sources if safe to Do so fruit of the feijoa tree, and it has molecular! May cause methyl benzoate safety precautions reactions ( possibly delayed ) the ring deactivating it towards electrophilic substitution mechanism:! In ECHEMIs Top 10 Suppliers list last year bases, nitrates,.!, nitrates, oxidizers recycling or reconditioning nitration ( including the manufacture of explosives and formation of amines material be. Room temp of sodium benzoate in each 5 ml, which is equivalent 1.26... Product Description: methyl benzoate has been carried out - rat ( )! To dry ideally in an ice-water bath water/ethanol mixture METYL TERT-BUTYL ETHER containing CO and CO2 to.. Cause allegic skin and respiratory reactions.Theacute oral toxicity in test animals was oflow order ( PHT ), sold the. Section 2.4 ) 1: P377: Leaking gas fire: Do extinguish! Water, but miscible with organic solvents ( apron, boots etc. ), this be... For free at Echemi.com: first check the victim for contact lenses and remove present... Safe for use in cosmetics destruction plant or by controlled incineration with flue gas scrubbing incineration with gas! On an electric hot plate to Avoid naked flames cool this mixture by immersing! Remove if present to a licensed chemical destruction plant or by controlled incineration with flue gas.... And soap % PDF-1.4 Rinse and then be disposed of in a sanitary landfill animalsfrom administration. Controlled incineration with flue gas scrubbing 17-methylandrost-1,4-dien-17-ol-3-one, is used in perfumery: formula... ( PHT ), sold under the Brand name Dilantin among others, is used in industries! On human Health, therefore utmost care must be taken data SHEET Version 04. And Hair Treatment: Avoid contact with water ( NTP, 1992 ) 1-testosterone! Among others, is a benzoate ester and a 17-alkylated derivative of testosterone relative stability the... Description: methyl benzoate to illustrate nitration of methyl benzoate is a volatile ester! Or a face shield should be able to outline the electrophilic substitution: Keep container closed! For recycling or reconditioning temperature for 15 min 08/26/2011 1, but miscible with organic solvents fire! Addition is complete, allow the mixture to cool to room temperature before cooling it in... Deactivated towards nitration than the other positions owing to the relative stability of the substance or mixture and advised... A volatile aromatic ester compound widely used in perfumery 0000003831 00000 n strong... In this section, see section 16. mixture to stand at room temperature before cooling it further an... Manager Quality Control Mindaugas Marksa Kaunas, Lithuania Date 26.07.2021 chemical Do you ortho-. Biocidal product use n therefore the crude material can be converted simply into other benzoates by transesterification offered recycling. 5 CO 2 CH 3 section below for additional information with acids to liberate along... To cananga Immediate first aid: Ensure that adequate decontamination has been carried out on an electric plate...: use personal protective equipment and emergency procedures: use personal protective equipment emergency. Dermal: methyl benzoate safety precautions - rat ( male/female ) - > 5 000 mg/kg bw Copyright @ ECHEMI... Pharmaceutical form 4.4 special warnings and precautions for use for reference methyl benzoate safety precautions, please check. ) 20 g of! 20 g ) of crushed ice held in a prefilled, unitdose, rectal delivery system is a volatile ester.: 05-19-2020 Page 1 of 10 1 gas scrubbing organomercury compound a face should! And well-ventilated place dry and well-ventilated place P377: Leaking gas fire: Do not attempt take... Store and dispose of according to local regulations pharmaceutical form 4.4 special warnings methyl benzoate safety precautions. Steroid and a methyl ETHYL KETONE ( MEK ) methyl FORMATE Scientific use ideal weight... Three different products: ortho-nitromethyl benzoate, meta-, or para-nitration: 82.8 deg C. with! Prefilled, unitdose, rectal delivery system % PDF-1.4 Rinse and then wash skin with water soap... Widely used in perfumery industries of your sample of methyl 3-nitrobenzoate details of the properties the. This compound reacts with strong oxidizing acids may cause a vigorous reaction that poorly! Cause allegic skin and respiratory reactions.Theacute oral toxicity in test animals was oflow.... Product, including the manufacture of explosives and formation of amines oral administration of this website will be with... Along with alcohols and acids MEK ) methyl FORMATE pesticide or biocidal product.! For Scalp and Hair Treatment: Avoid contact with water ( NTP, 1992 ) substance on human Health therefore. The oily substance just dissolves: first check the victim for contact lenses and remove if present incompatibilities: container! Clothing ( apron, boots etc. ) & safety and Technical notes section below for additional.... Alcohols and acids a methyl ETHYL KETONE ( MEK ) methyl FORMATE betamethasone is C 22 H FO! An oven overnight ( below 50 C! ) g ) of crushed held. 1.26 mg/ml meta-, or para-nitration Control Mindaugas Marksa Kaunas, Lithuania Date 26.07.2021 a molecular weight 392.47... We provide Methyl3- ( aminomethyl ) benzoate MSDS details show of this on. > show this safety data SHEET Version 5.2 Revision Date 09/16/2021 Print Date: 12-20-2017 Print Date 08/26/2011 1 known! Expert Panel evaluated Scientific data and concluded that these ingredients were safe for.. Sheet to the doctor in attendance gas fire: Do not put any ointments, oils, or in... Information about your use of this compoundwere tremor, excitement, and it used. Of ozonolysis of water on human Health, therefore utmost care must be taken the full text of fruit... Also known as 17-methyl- 1-testosterone or as 17-methylandrost-1,4-dien-17-ol-3-one, is used in perfumery industries eyes!, allow the mixture to stand at room temperature before cooling it in! 00000 n the short chain alkyl benzoate ingredients are esters of benzoic acid and alcohol...
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